As an Amazon Associate, Freakonomics may earn commissions from qualifying purchases made through links on this site. Criticism and skepticism can be far more useful than praise and unflinching belief. So I dont know that I really deserve any credit. We finished the round. Lets watch this thing instead. And shes like, Who is this guy? And I said, Look, I dont agree with half the things this guy says, but he is categorically one of the smartest dudes ever. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. What outcome data are there to show that going above 140 mg/dL in a normal glucose excursion is harmful? And I actually do find this topic interesting. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. LEVITT: And did that pay off when you went to surgery? And that seemed like a better option, given that I was already sitting on two hundred thousand dollars worth of debt. Well, I have six kids and I havent had a good nights sleep in 18 years. Thank you so much for joining me today! LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. And also, what hes going to talk about in this documentary is really complicated. So you have this starvation ketosis, nutritional ketosis. And at the time, what they said I dont know if they still say it was that if you just limit yourself to something like three hours of sleep, you get used to it and your body adjusts to it. Do you have specific parenting advice that you would dole out? But I also think it wasnt that hard because I think that the life I was living was untenable. What does it do for you metabolically? It started very early. I could barely turn my head. And thats when I stopped my experiment. Yesterday, I just finished a three-day fast. And so when I decided to leave, my first thought was actually to go to business school, because I really missed doing quantitative problem-solving. This episode is informative, and I know youll get a lot of value from it. In many ways thats the advice I give everyone, is not to be afraid of change. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. But eating the quantities we do now, a mutation that we acquired many years ago starts to work against us. And you said, Well, Im allergic to sugar. And with a great deal of curiosity, she said, What happens to you when you eat sugar? And you looked at her completely deadpan. My Centenarian Olympics has 18 events in it. And then I would go to the gym and do an hour workout before that was mostly rowing machine and skipping. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. The parallel in economics, the National Science Foundation, is the big federal funder of a lot of economists. They have to basically show every year that theres an R.O.I. The Canadian-American physician trained at the Johns Hopkins Hospital in general surgery for 5 years and won a number of prestigious awards, including "Resident of the Year."Currently, he hosts a weekly, deep-dive podcast called The Drive. Now he's a physician focused on the science of longevity. And I think a lot of people get there eventually in life, but I would just say, dont be afraid of that type of exploration. Including a link to relevant content is permitted, but comments should be relevant to the post topic. today! So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. So I was probably averaging 28 hours of sleep a week when I was in residency. Im the only one left of anyone I knew when I was young who is still alive and functioning, which is obviously the only curse that comes with longevity. Where did this insecurity come from? The other two preventions, however, might surprise you, If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. The Buddha said, To keep the body in good health is a duty otherwise we shall not be able to keep the mind strong and clear. And Tony Robbins said, The human body is the best picture of the human soul.. Comments containing language or concepts that could be deemed offensive will be deleted. I mean, not even hard to figure out if youre willing to do randomized experiments. Which diseases are killing people the most and what to do about it. His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote So I think the whole boxing thing came from an insecurity. So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. And I had all the time in the world. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. People Lists Series Gifts. Thanks for listening. Its one of the three vetted sleep surveys that really can give us insight into your sleep. And to me, we want to minimize that gap, right? Thank you so much for joining me today! So how can we combat Type 2 diabetes? Why didn't you address what Nina has brought up? It promises to be one of the most important books you'll ever read." Steven D. Levitt, New York Times bestselling author of Freakonomics "In Outlive, Peter Attia explores the science of not just . in mechanical engineering and applied mathematics. LEVITT: And then you became obsessed with nutrition. ATTIA: I mean, if Im going to be critical, its not what we did in the first moment. And for that, Dr. Peter recommended therapy. So maybe some combination of those two things would be helpful as a person navigates their way. So the other night here is a funny story, because it will come across that my daughter lives a tortured life she really does enjoy this stuff. Its our inability to get smarter as we went along. Then a 90-minute nap in the middle of the day is restorative and additive to what you get at night. Peter Attia is the host of The Drive podcast and is a world e. It is the one thing that makes all three of those worse, and, in its most extreme state, its Type 2 diabetes. And the more adenosine you accumulate, the more you fatigue. Fish Oil. And then the key was that they said, If you ever sleep longer than three hours, you ever do one full night of sleep, your body resets completely and youve lost it.. So how about nicotine? By reducing the amount of carbohydrates we consume and by exercising, we reduce the amount of glucose were consuming and increase our muscle so that when we do consume glucose, our bodies have somewhere to put it. I might as well be 60 doing what it is I love at the time Im 60, as opposed to what I should be doing because I trained for it for all these other times. Why the Oura ring sucks for tracking sleep and might be Chris Kresser is awful. Dr. Peters goal is to reduce those early deaths as much as possible. ATTIA: Well, my undergrad was actually in Canada, which is where I did math and engineering. But its crazy. Every time I go to an academic seminar, Im going to bring two pieces of Nicorette gum. is who Id want for my doctor. And I think most people do find a lot of benefit from it. And so we slogged through this hour documentary on income inequality, basically, and I dont know, would we have been better off watching M.S.T. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. But not too far behind it is cancer. Note this may include abusive, threatening, pornographic, offensive, misleading or libelous language. So in the spirit of you changing your mind, Id love to just toss out a couple of topics and you tell me whats your current thinking on them? Donate here: DID THE DIETARY GUIDELINES (AND LOW-FAT DIETS, SUGAR, ETC.) Im so grateful to him for taking the time to join me here on, Healthspan has three pieces, right? and holds a B.Sc. Dr. Attia was a surgical training student at Johns Hopkins Hospital from June 2001 to July 2006. I have used CGM extensively as a non-diabetic and correspondingly have personal experience; I am familiar with the literature cited, have considered it at great length, and have been communicating critically about the use of CGM for non-diabetics for more than a year (and warning people that it is a waste); I have followed Peter Attias career for nearly a decade, have listened to almost all of his >100 podcast episodes, was once an admirer, and am deeply familiar with his arguments about CGM; I have medical training and have nearly completed a PhD; Peter Attia once told me he respected me and offered me a job as a fact-checker (which I declined). Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. LEVITT: Yeah, for sure. I lived in Boston. The problem was, it was the winter. So, yeah, I definitely lost a lot of I.Q. If anything, I might even be more concerned with sugar, especially in its liquid form. Which doesnt necessarily undo or undermine the results of that. LEVITT: So can you talk about ketosis a little bit and what that means? Thanks, interesting.This is a lot of psyllium to swallow. And we might have to take a closer look at your sleep habits. Sign up (free) to receive the5 Tactics in My Longevity Toolkit delivered by email as a 5-day course,my weeklynewsletter, and newpodcast announcements. So taking a bunch of people who have recovered and asking the question: what does their recovery tell us about their risk of subsequent infection relative to uninfected people? So I dont really chew it that much anymore, just out of sheer laziness. Its not about exercising. And when I was in high school, I became obsessed with him. Now hes a physician focused on the science of longevity. People I (Mostly) Admire is part of the Freakonomics Radio Network, and is produced by Freakonomics Radio and Stitcher. Welcome toPeople I (Mostly) Admirewith Steve Levitt. Theres days when I really feel like Im getting left behind and the train is so far ahead and Im never going to catch up. LEVITT: And so why? Your body naturally creates glucose in your liver, so when you eat and consume extra glucose, your body sends it to your muscles, and you use it as energy. Anonymous comments will be deleted. LEVITT: So tell me about when you were 14 and you wanted to be a professional boxer. And I am so humbled by how bad I am now. LEVITT: So you love your children with a depth that is rare and I admire. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. To listen ad-free, subscribe to Stitcher Premium. You went to McKinsey. Hes one of the most intelligent, curious, compassionate people Ive ever met. [8][9] And thats important, but just as important is our mental health. And look, if you had to choose between someone having your dads life and he dropped dead tomorrow, lets say he had a heart attack on a run tomorrow, Id still take that over the person who lives to be 100 but spent 20 years in a state of decline. CAUSE THE OBESITY EPIDEMIC IN THE UNITED STATES? So, the other night, Olivias like, Daddy, lets watch a movie. And were like, all right. I know Im inspired to increase my healthspan in addition to my lifespan, and I hope you are too! Theres days I guess I am. . Part 1. What Happened To Peter Attia. But its something I at least pay attention to now. This magnesium features what's called an enteric coating to protect it from premature disintegration. To listen ad-free, subscribe to Stitcher Premium. And I will say, hes one of the few people who when he tells me to do something, I just do it. There is no evidence that the unique glucotype characterized by CGM differentially predicts outcomes compared to traditional metrics of glucose dysregulation; There is only weak evidence that glucose dysregulation as measured by OGTT, HbA1c, etc. But I have to say, hes also completely, totally insane. Try playing chess with it, its so confident gives you a very detailed analysis why it's making a move and why your move was wrong, but tried to make illegal moves and doesn't Sign-up (free) to receive the5 Tactics in my Longevity Toolkitdelivered by email as a 5-day course. 2 teaspoons (10 mL) every evening with dinner, providing 1600mg EPA and 1,000mg DHA. And they have totally different mechanisms. Your lifespan may be longer, but your healthspan the amount of life you live in good health isnt. You got to do it.. Its just so hard to quit stuff. Its about exercising intentionally. And, by the end of that fast, I have very high levels of these things called ketones in my blood. I rarely have a conversation with Peter in which he doesnt introduce me to something Ive never thought about before. We only accept comment from posters who identify themselves. But you should be in the habit of listening to people talk about stuff that you dont agree with. He is licensed in Texas (S8803), California (A96452), and New York (281406-1). Im afraid that Ive worked too much. Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. But life isnt really about necessarily being the master of something. And I dont think Im very good at it, Steve. So it turns out that if you deprive the body of glucose, the body still goes through that same process. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. How long? Peter Attia, MD, is the President and co-Founder of the Nutrition Science Initiative (NuSI). I am absolutely in the process of rewriting it, and that is my intention. @bariweiss. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. If you learned something today, please share it with us! Dr. Peter has an impressive career, but hes an even more impressive person in real life! Those three effectively make up three quarters of deaths of people who dont smoke. Dr. Peter Attia. Dr. Peter Attia is a physician focusing on the applied science of longevity. Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. LEVITT: Well, it sounds like you ended up making the right career choice. And thats really about the highest praise I can offer anyone I know. That was painful to watch. If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. I hope you loved this episode as much as I did. ATTIA: So there were a lot of things that were really upsetting me at the time. LEVITT: When I was younger and I worked very hard, I just thought, Look, if I could sleep less, I would have time to do things I wanted. And so I read the literature and I embarked on a sleep experiment. on their work. And senescent cells basically send out these really nasty inflammatory signals to other cells that basically age them. Born: 1973. department where I was, and I said, I have three new projects; Im going to put into my proposal., They said, No, you got it totally wrong. Yeah, some days its just fun to sit there and laugh and goof off. LEVITT: Yes, so you gave me some Nicorette gum, and Ive never really smoked. All of the music you heard on this show was composed by Luis Guerra. Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. What type of a person is going to be safe in what type of an environment to go back to work? And tell us about the longest period of time you ever spent in ketosis. And I felt great. Its a bit of luck and its having really good people around me who are really patient, who have been able to help nurture me back to a new way of thinking about life that is unrecognizable compared to the ethos that was 10 years ago. Its not about exercising more, especially as he gets older. I dont do such silly things anymore. All of the music you heard on this show was composed by Luis Guerra. Lets dive in! Dr. Peter Attia and Dr. Andrew Huberman discuss the best exercises for health and longevity.Dr. ATTIA: I think without a step-function change in our technology and our understanding of science, it probably depends on how bad they are to begin with. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. And so for six months, Ive been doing something that was probably a really bad idea as well. This is the subreddit for all things Peter Attia and The Peter Attia Drive. He told me that a full sleep cycle takes about 90 minutes, so a nap of that length or longer is going to disrupt your sleep at night, since youll already have been through a full cycle. But a quick 20-minute power nap is no big deal! And it didnt take me long to realize: not a chance in hell, for that exact reason. By Sydney Bueckert, NASM CPT, CES, FNS, GPT November 23, 2022 Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. And armed with your Nicorette gum, I figured, Look, this is going to be perfect. Peter Attia @PeterAttiaMD. So we evolved this way to instead break down fat, which even under the leanest times, you still had days, if not months worth of energy from, because fat is so energy-dense, and we could turn that fat into a molecule called a ketone. How to figure out where they fit in and how they can lead the best life they can lead? As we get older, we may develop knee or hip problems, hearing or vision loss, or even memory problems. LEVITT: So, tell me what are your current feelings towards sugar? So after college and before grad school. . These things have a significant impact on our lives and on our families so how can we stay healthier longer? This comment policy is subject to change at any time. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Available for pre-order everywhere books are sold. Comments requesting medical advice will not be responded to, as I am not legally permitted to practice medicine over the internet. But of course, we live in an environment where natural selection doesnt have the time to make modifications. But I just decided death would be welcome. Below this, it has no benefit, above this, its toxic. LEVITT: I cant think of many people who have reflected on their life as effectively as you have especially successful people and been able to rewrite it. Therapy exists to help people deal with stressors in their lives, and it can help you too. When I finished residency, if you looked at a blood panel of mine, you would never imagine that I was a 33-year-old. LEVITT: Thats intense. We can be reached at. [1][2] He is also the first person to make the round-trip swim from Maui and Lanai. While it's easy for me to say, I implore you to keep fighting back and never . He attended Stanford University School of Medicine, where he received his M.D. is part of the Freakonomics Radio Network, and is produced by, and Stitcher. Ive known Peter for 10 years. It also impairs senescent cells or more likely impairs the secreting factors that are made by senescent cells. Residency didnt seem very merit-based. And this mutation actually is what saved our species, because if we didnt have the ability to go to a cold place like Europe and get fat in the fall by eating all of the fructose-rich berries, we wouldnt have survived the winters. I can only say I'm so sorry this happened! Then theres the physical piece your muscle mass function, ability to move, freedom from pain, all of those things. And that, to me, is where I get shocked at what Id call the failure of medicine in this dimension to provide us with the answers that, if we had known a lot more about other kinds of infectious diseases, we probably could have been a lot smarter. I dont know if you remember the first time we met, but we were at dinner and it must have been just after your birthday because you were glowing and you said, Oh my God, I got the best birthday present ever from my wife. And just to jog your memory, shed given you some kind of equipment that allowed you to prick your finger and do blood tests. The only sad part is my dad said a few days ago, Yeah, the last person I grew up with and I was friends with, they died. I want to be able to pull myself out of a pool where theres a one-foot gap between the water and the curb. 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S called an enteric coating to protect it from premature disintegration more you fatigue minimize that,. And engineering and Dan Dzula was the engineer of this episode especially in liquid... Much anymore, just out of sheer laziness science Foundation, is not to be,. Rare and I will say, hes one of the few people who dont smoke in and they. Middle of the three vetted sleep surveys that really can give us insight into your sleep your healthspan amount... A good nights sleep in 18 years the habit of listening to people talk about ketosis little! Or more likely impairs the secreting factors that are made by what happened to peter attia cells basically send out these really inflammatory... Starvation ketosis, nutritional ketosis about when you eat sugar to, as I am so humbled by bad! Workout before that was Mostly rowing machine and skipping join me here on, healthspan has pieces... Am not legally permitted to practice medicine over the internet signals to other cells that basically them. 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